The star has donated the complete sum of his twenty-five thousand pound award winnings to the MVT, which works to protect the Britain's grassroots live music spots.
He was awarded the cheque on October 16 as his latest record the album was named the best record of the last 12 months.
Fender has opted to give the cash to the Music Venues Trust, in appreciation of the vital role local spots played in his beginning days.
"I couldn't be pursuing what I am doing today if it weren't for all the gigs I performed around the region, and elsewhere, when I was beginning," said the artist. "These venues are legendary, but they are in difficulty."
Since the start of 2023, more than 150 of these locations have permanently closed – approximately 16 percent of the entire UK sector.
Over the past year, top acts like Pulp, the group Coldplay, Katy Perry and Sheeran have all supported the trust in its efforts to support the industry, by adding a small levy to their ticket costs, which goes to help independent venues.
He also took part, raising in excess of £100,000 on his live tour to assist thirty-eight grassroots venues across the UK.
The money helped spaces that were dealing with possible closure due to issues arising from water damage, fire incidents and family tragedies, as well as regulatory hurdles, legal disputes and neighbor objections.
Some locations were granted financial assistance in improving amenities and technical equipment that helped musicians and fans.
"The notion that funds from concerts in big venues backs the local stages, where it begins for musicians like me, is just logical," Sam Fender has said.
The musician is far from the only musician to give his Mercury Prize prize money to worthy causes.
In Pulp earned the prize in 1996 for their album Different Class, lead singer Cocker stated that the band would contribute their winnings to the charity the charity.
That year, rapper and singer she shared her prize between multiple good causes, such as the children's charity and a charity for Sickle Cell.
"And I donated a grand to my local community centre, to their gymnastics program, because I trained in gymnastics when I was a child and they needed updated gear," she shared with the media.
Previously, Ezra Collective donated their winnings to the youth organization that nurtured their group, as well as other grassroots music organisations.
Also 1994 winners the group contributed their award to a multiple sclerosis charity after a close contact was found to have the illness.
"The victory was quite enough," remarked vocalist Small. "The money was the bonus but we didn't require the cherry, because we had the honor. So our victory touched the lives of others."
Last week, the MVT shared it had protected a couple of local spots in the South East, by placing them under public stewardship.
The Joiners in the city and The Croft in that location were purchased under the Own Our Venues initiative, which is funded by a national body and enthusiasts who acquire "shares" in the buildings.